By Jose de Leon (auth.), Jose de Leon (eds.)

Emotional, behavioral, and neuropsychiatric stipulations are universal in people with highbrow disabilities (IDs), so much significantly epilepsy, aggression, self-injurious behaviors, and bipolar and different temper issues. regardless of the superiority of such difficulties, there's a shortage within the literature of trustworthy info on clinical remedies for people with IDs.

A Practitioner's advisor to Prescribing Antiepileptics and temper Stabilizers for Adults with highbrow Disabilities presents a close framework for prescribing for this not easy inhabitants. that includes the main up to date details on components that tell prescribing, the Guide addresses uncomplicated matters and controversies (e.g., the rift among evidence-based and customized drugs) in treating adults with cognitive deficits. consumers' particular wishes are emphasised in constructing applicable and potent pharmacological intervention for better results and caliber of existence. medications mentioned within the Guide comprise carbamazepine, clonazepam, diazepam, ethosuximide, felbamate, gabapentin, lacosamide, lamotrigine, levetiracetam, lithium, lorazepam, oxcarbazepine, phenobarbital, phenytoin, pregabalin, primidone, rufinamide, tiagabine, topiramate, valproate, and zonisamide. for every of those compounds, the tips cover:

  • Indications to be used; relative and absolute contraindications.
  • Assessment in the course of therapy; healing drug tracking; indications and indicators for caretakers.
  • Dosage: management; preliminary and greatest suggested dosage; alterations linked to drug-drug interactions, own features, and (where acceptable) genetic variations.
  • Adverse drug reactions: universal, quite unusual, and almost certainly deadly, plus threat of metabolic syndrome.
  • Guidelines for discontinuation.
  • References, tables, and drug usage reviews.

A Practitioner's advisor to Prescribing Antiepileptics and temper Stabilizers for Adults with highbrow Disabilities is an essential decision-making reference for psychiatrists, neuropsychologists, psychopharmacologists, neurologists, internists, and medical psychologists.

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Extra info for A Practitioner's Guide to Prescribing Antiepileptics and Mood Stabilizers for Adults with Intellectual Disabilities

Sample text

Clinical Drug Investigation, 16, 263–277. , & Seidel, M. (2006). Update on treatment of epilepsy in people with intellectual disabilities. Current Opinion in Psychiatry, 19, 492–496. , & Tomka-Hoffmeister, M. (2003). Limited efficacy of gabapentin in severe therapyresistant epilepsies of learning-disabled patients. Seizure, 8, 602–603. , Koepp, M. , Sander, J. , & Thompson, P. J. (2006). The impact of levetiracetam on challenging behaviour. Epilepsy & Behavior, 8, 588–592. , & Helle, E. P. (1977).

Yoon, C. , Rothschild, J. , Kachalia, A. , Churchill, W. , Whittemore, A. , Bates, D. , & Gandhi, T. K. (2010). Effect of bar-code technology on the safety of medication administration. The New England Journal of Medicine, 362, 1698–1707. 16 1 Introduction Reid, A. , Naylor, G. , & Kay, D. S. G. (1981). A double-blind, placebo controlled, crossover trial of carbamazepine in overactive, severely mentally handicapped patients. Psychological Medicine, 11, 109–113. , & Himlok, K. (2009). How is epilepsy treated in people with a learning disability?

The guidelines focus on the oral formulations. The nonoral antiepileptic formulations are described in Chap. 23. 1 Evidence-Based Medicine A prior guideline (de Leon et al. 2009) explained in detail that we live in the era of evidence-based medicine. Treatment information provided by evidence-based medicine is systematically biased by pharmaceutical companies, and by lack of evidence as it relates to chronic conditions. These limitations are particularly relevant for the treatment of individuals with IDs.

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