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Tablets containing promethazine hydrochloride 20mg.

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Information about Promethazine.

Promethazine hydrochloride tablets are contraindicated for use in pediatric patients less than two years of age.

Promethazine hydrochloride occurs as a white to faint yellowpractically odorlesscrystalline powder which slowly oxidizes and turns blue on prolonged exposure to airIt is soluble in water and freely soluble in alcohol.

How often you take this medicine and the timing of your dose will depend on the condition being treated.

CNS DepressantsPromethazine hydrochloride tablets may increaseprolongor intensify the sedative action of other central-nervous-system depressantssuch as alcoholsedatives/hypnoticsincluding barbituratesnarcoticsnarcotic analgesicsgeneral anestheticstricyclic anti-depressantsand tranquilizersthereforesuch agents should be avoided or administered in reduced dosage to patients receiving promethazine HClWhen given concomitantly with promethazine hydrochloride tabletsthe dose of barbiturates should be reduced by at least one-halfand the dose of narcotics should be reduced by one-quarter to one-halfDosage must be individualizedExcessive amounts of promethazine HClpromethazine hydrochloriderelative to a narcotic may lead to restlessness and motor hyperactivity in the patient with painthese symptoms usually disappear with adequate control of the pain.

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